How does actos work

While Actos markets itself based on the idea that it can lower and control glucose levels, the list of side effects would simply astonish you. Some of the major side effects include stomach pain, blood in urine, swelling or rapid weight gain, nausea, blurred vision, pale skin, easy bruising, general weakness, headaches, weight gain, back pain, and even tooth pain.

Find various treatment options for diabetes at online health care. Lawrence Kindo. I am a Medical Professional with a passion for writing, blogging, playing, computers, and of course patient care.

In animal studies , animals that were given Actos did have the drug present in their breast milk. They can review the best ways to feed your child and your medication options.

This drug has a boxed warning. A boxed warning alerts doctors and patients about drug effects that may be dangerous. This can cause fluid to build up in your body. Symptoms of CHF include quick weight gain; trouble breathing; and swelling, especially in the legs and feet. Your doctor will monitor you for symptoms of CHF after you start taking Actos and if they increase your dose. If you develop CHF while taking Actos, your doctor may decrease your dose or have you stop taking the medication.

These are more serious classes of heart failure. Before taking Actos, talk with your doctor about your health history. Actos may not be right for you if you have certain medical conditions or other factors affecting your health.

Using more than the recommended dosage of Actos can lead to serious side effects. There was one case of someone taking too much Actos in clinical trials. However, no symptoms of overdose were reported. You can also call the American Association of Poison Control Centers at or use their online tool. But if your symptoms are severe, call or go to the nearest emergency room right away.

When you get Actos from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically 1 year from the date they dispensed the medication. The expiration date helps guarantee that the medication is effective during this time. If you have unused medication that has gone past the expiration date, talk with your pharmacist about whether you might still be able to use it. How long a medication remains good can depend on many factors, including how and where you store the medication.

Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. It should be protected from humidity and moisture. This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment. This article provides several useful tips on medication disposal. You can also ask your pharmacist for information on how to dispose of your medication.

Actos is indicated for use in the treatment of adults with type 2 diabetes. It should not be used to treat patients with type 1 diabetes or with diabetic ketoacidosis. Actos belongs to a class of medications called thiazolidinediones. These drugs work by acting on peroxisome proliferator-activated receptor PPAR gamma. PPAR gamma is a receptor that is responsible for controlling insulin sensitivity.

Actos works by agonizing PPAR gamma, which then gets rid of glucose in the body by decreasing insulin resistance. Actos is dependent on the presence of insulin to work properly. This is why it is not indicated for use in type 1 diabetes.

Actos takes about 2 hours to reach maximum concentration after a dose. Taking Actos along with food may make the medication absorb more slowly about 3 to 4 hours to maximum concentration. However, this does not change the overall absorption of the drug. Steady-state levels of Actos are reached about 7 days after once-daily dosing. Actos is mainly hydroxylated and oxidated in the liver. Excretion occurs in the bile of the liver.

The half-life of Actos is between 3 and 7 hours. The half-life of the major metabolites of Actos is between 16 and 24 hours. This is because Actos can cause new onset or worsening heart failure. If a patient already has severe heart failure, using Actos is contraindicated. Actos is also contraindicated in patients with a history of allergic reaction to pioglitazone or any excipients in the Actos tablet. Actos tablets should be protected from humidity and moisture. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date.

However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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In people with type 2 diabetes, beta cells, which help produce and release insulin, need to work harder and may become damaged over time. Learn more. Actos pioglitazone. Medically reviewed by Dena Westphalen, Pharm. What is Actos? Actos generic. Actos side effects.

Actos dosage. Common questions about Actos. Actos uses. Alternatives to Actos. Actos vs. Actos interactions. How to take Actos. How Actos works. Actos use with other drugs.

Actos and alcohol. Actos cost. Actos and pregnancy. Actos and birth control. Why pioglitazone is banned? Indian drug regulatory authorities withdrew pioglitazone in June but then revoked the ban due to lack of sufficient evidence and recommendation by the Drug Technical Advisory Board DTAB 3.

The EMA assessed the association of pioglitazone with bladder cancer. Does Actos cause leg swelling? Pioglitazone Actos and rosiglitazone Avandia are medications used to treat type 2 diabetes. Leg swelling is a well-known side effect of both meds, so if you experience swelling while taking them, ask your doctor about switching to another medication.

Is Actos the same as metformin? Actos is used for the treatment of type 2 diabetes in adults. Actos may be used alone or in combination with metformin Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet , a drug in a different class of anti-diabetic drugs, that also lowers blood glucose.

Does Actos cause water retention? Up to 75 percent of the increase in body weight that can occur in patients with type 2 diabetes who are treated with pioglitazone is from water retention but the drug also tends to reduce abdominal fat and blood pressure.

Can you take Actos and metformin together? Metformin and pioglitazone is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus who do not use daily insulin injections.

Metformin and pioglitazone may also be used for purposes not listed in this medication guide. Insulin and Diabetes What Is Insulin? Is Afrezza Safe for Your Lungs? Ozempic Rybelsus Trulicity. Amaryl Glucotrol. Farxiga Invokana. Actos Avandia. Welcome to the Learning Center! Here you will find everything that you need to know about Diabetes. What Is Diabetes? How Many Have Diabetes? Is There a Cure? Famous People with Diabetes.